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Papers: 13 Jul 2024 - 19 Jul 2024


2024 Jul 16


Immunopharmacol Immunotoxicol


39013842

Attenuation of adjuvant-induced arthritis with carnosic acid by inhibiting mPGES-1, COX-2, and bone loss in male SD rats.

Authors

Shrivastava S, Bahuguna T, Mondal S, Kumar S, Mathew B, Jeengar MK, Naidu VGM

Abstract

Rheumatoid arthritis (RA), a chronic inflammatory disease, is characterized by joint swelling, cartilage erosion, and bone destruction. This study investigated the therapeutic efficacy of Carnosic acid (CA), a natural compound with anti-inflammatory and antioxidant properties, in an adjuvant-induced arthritis model.