Establishment of a Posttraumatic Osteoarthritis Model in Mice Induced by Noninvasive Anterior Cruciate Ligament Tear.
Authors
Okazaki Y, Nakagawa Y, Deng XH, Zhang X, Wada S, Album Z, Ying L, Rodeo SA
Abstract
Animal models that use open surgical transection of the anterior cruciate ligament (ACL) do not accurately simulate the clinical condition regarding the pivot-shift mechanism and the associated inflammatory response that occurs before reconstruction.
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