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Papers of the Week
Network analysis of monoamines involved in anxiety-like behavior in a rat model of osteoarthritis.
Authors
Mlost J, Białoń M, Kędziora M, Wąsik A, Michalec Ż, Starowicz KAbstract
Chronic pain is a major health problem that affects a significant number of patients, resulting in personal suffering and substantial health care costs. One of the most commonly reported causal conditions is osteoarthritis (OA). In addition to sensory symptoms, chronic pain shares an inherent overlap with mood or anxiety disorders. The involvement of the frontal cortex, striatum and nucleus accumbens, in the affective processing of pain is still poorly understood.