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Papers of the Week


Papers: 16 Dec 2023 - 22 Dec 2023


2023 Dec 15


Biol Psychiatry


38104648

Chronic morphine leaves a durable fingerprint on whole brain functional connectivity.

Authors

Sourty M, Champagnol-Di Liberti C, Nasseef MT, Welsch L, Noblet V, Darcq E, Kieffer BL

Abstract

Opioid use disorder (OUD) is a chronic relapsing disorder. The brain adapts to opioids along pain treatment or recreational use, so that abstinence becomes a true challenge for individuals with OUD. Studying brain dysfunction at this stage is difficult, and human neuroimaging provides highly heterogenous information.