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Papers of the Week
Integration of microbiota and metabolomics reveals the analgesic mechanisms of emodin against neuropathic pain.
Authors
Wang C, Wu L, Zhou R, Song C, Chen P, Huang S, Ali Khan A, Lu D, Hu Y, Chen LAbstract
Neuropathic pain (NeP) induced dysbiosis of intestinal microbiota in chronic constriction injury (CCI) rats. Emodin has analgesic effect but the detailed mechanism is not clear at the present time. This study aims to explore the underling mechanism of action of emodin against NeP with in CCI model.