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Papers of the Week
Astrocyte senescence-like response related to peripheral nerve injury-induced neuropathic pain.
Authors
Du J, Cheng N, Deng Y, Xiang P, Liang J, Zhang Z, Hei Z, Li XAbstract
Peripheral nerve damage causes neuroinflammation, which plays a critical role in establishing and maintaining neuropathic pain (NeP). The mechanisms contributing to neuroinflammation remain poorly elucidated, and pharmacological strategies for NeP are limited. Thus, in this study, we planned to explore the possible link between astrocyte senescence and NeP disorders following chronic sciatic nerve injury.