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Papers of the Week


Papers: 12 Aug 2023 - 18 Aug 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Abdominal/Pelvic Pain, Inflammation/Inflammatory


2023


J Inflamm Res


37576154


16

Resolvin D1 Attenuates Inflammation and Pelvic Pain Associated with EAP by Inhibiting Oxidative Stress and NLRP3 Inflammasome Activation via the Nrf2/HO-1 Pathway.

Authors

Zhang J, Chen J, Jiang Q, Feng R, Zhao X, Li H, Yang C, Hua X

Abstract

Resolvin D1 (RvD1), a member of the specialized pro-resolving lipid mediators family, has a potent anti-inflammatory effect and alleviates tissue damage. The purpose of the current research was to study the effect of RvD1 on CP/CPPS and the underlying mechanisms using a mouse model of experimental autoimmune prostatitis (EAP) mice.