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Papers of the Week


Papers: 3 Jun 2023 - 9 Jun 2023

RESEARCH TYPE:
Clinical


Human Studies, Molecular/Cellular, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Arthritis, Inflammation/Inflammatory


2023 Jun


Osteoarthr Cartil Open


37284460


5


2

The OA Trial Bank: Update of individual patient data meta-analysis of intra-articular glucocorticoids in persons with knee and hip osteoarthritis.

Authors

Yu SP, van Middelkoop M, Ferreira ML, Deveza L, Bierma-Zeinstra SMA, Venkatesha V, Hunter DJ

Abstract

To evaluate the efficacy of intra–articular (IA) glucocorticoid for knee or hip osteoarthritis (OA) in specific subgroups of patients according to the baseline severity of pain and inflammatory signs using individual patient data (IPD) from existing trials. Furthermore, this study aims to assess if a baseline pain cut-off was associated with clinically important effectiveness of IA glucocorticoid. This is an update of an IA glucocorticoid IPD meta-analysis by the OA Trial Bank.