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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury.

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Papers: 4 Mar 2023 - 10 Mar 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Molecular/Cellular, Pharmacology/Drug Development

PAIN TYPE:
Inflammation/Inflammatory, Neuropathic Pain


2023


Front Mol Neurosci


36873101


16

Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury.

Authors

Han J, Hua Z, Yang WJ, Wang S, Yan F, Wang JN, Sun T

Abstract

Neuropathic pain (NP) is one of intractable complications of spinal cord injury (SCI) and lacks effective treatment. Resveratrol (Res) has been shown to possess potent anti-inflammatory and anti-nociceptive effects. In this study, we investigated the analgesic effect of Res and its underlying mechanism in a rat model of SCI.
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