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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Spinal protein kinase A and phosphorylated extracellular signal-regulated kinase signaling are involved in the antinociceptive effect of phytohormone abscisic acid in rats.

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2020 Jan 31


Arq Neuropsiquiatr


http://www.ncbi.nlm.nih.gov/pubmed/32022118?dopt=Abstract

Spinal protein kinase A and phosphorylated extracellular signal-regulated kinase signaling are involved in the antinociceptive effect of phytohormone abscisic acid in rats.

Authors

Spinal protein kinase A and phosphorylated extracellular signal-regulated kinase signaling are involved in the antinociceptive effect of phytohormone abscisic acid in rats.
Mollashahi M, Abbasnejad M, Esmaeili-Mahani S
Arq Neuropsiquiatr. 2020 Jan 31.
PMID: 32022118.

Abstract

The phytohormone abscisic acid (ABA) as a signaling molecule exists in various types of organisms from early multicellular to animal cells and tissues. It has been demonstrated that ABA has an antinociceptive effect in rodents. The present study was designed to assess the possible role of PKA and phosphorylated ERK (p-ERK) on the antinociceptive effects of intrathecal (i.t.) ABA in male Wistar rats.
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