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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Is Spreading Depolarization a Risk Factor for Late Epilepsy? A Prospective Study in Patients with Traumatic Brain Injury and Malignant Ischemic Stroke Undergoing Decompressive Craniectomy.

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2020 Sep 30


Neurocrit Care


http://www.ncbi.nlm.nih.gov/pubmed/33000378?dopt=Abstract

Is Spreading Depolarization a Risk Factor for Late Epilepsy? A Prospective Study in Patients with Traumatic Brain Injury and Malignant Ischemic Stroke Undergoing Decompressive Craniectomy.

Authors

Is Spreading Depolarization a Risk Factor for Late Epilepsy? A Prospective Study in Patients with Traumatic Brain Injury and Malignant Ischemic Stroke Undergoing Decompressive Craniectomy.
Sueiras M, Thonon V, Santamarina E, Sánchez-Guerrero Á, Riveiro M, Poca M-A, Quintana M, Gándara D, Sahuquillo J
Neurocrit Care. 2020 Sep 30.
PMID: 33000378.

Abstract

Spreading depolarizations (SDs) have been described in patients with ischemic and haemorrhagic stroke, traumatic brain injury, and migraine with aura, among other conditions. The exact pathophysiological mechanism of SDs is not yet fully established. Our aim in this study was to evaluate the relationship between the electrocorticography (ECoG) findings of SDs and/or epileptiform activity and subsequent epilepsy and electroclinical outcome.
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