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Papers of the Week


2020 Oct 26


Chest

Obstructive Sleep Apnea patients adhering to Continuous positive Airway Pressure: A randomized trial.

Authors

Pépin J-L, Georgiev O, Tiholov R, Attali V, Verbraecken J, Buyse B, Partinen M, Fietze I, Belev G, Dokic D, Tamisier R, Lévy P, Lecomte I, Lecomte J-M, Schwartz J-C, Dauvilliers Y
Chest. 2020 Oct 26.
PMID: 33121980.

Abstract

Excessive daytime sleepiness (EDS) in individuals with obstructive sleep apnea syndrome persisting despite good adherence to continuous positive airway pressure (CPAP) is a disabling condition. Pitolisant is a selective histamine H3-receptor antagonist with wake-promoting effects.