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Papers of the Week


2022 Mar 11


Phytomedicine


100

Ginsenoside-Rb1 prevents bone cartilage destruction through down-regulation of p-Akt, p-P38, and p-P65 signaling in rabbit.

Authors

Hossain M A, Jahangir Alam M, Kim B, Kang C-W, Kim J-H
Phytomedicine. 2022 Mar 11; 100:154039.
PMID: 35344713.

Abstract

Osteoarthritis (OA) is the most common joint complaint resulting in pain, disability, and loss of quality of life. On the other hand, ginsenoside-Rb1 is a plant product derived from ginseng that possesses immune-regulation and anti-inflammatory activities. However, it has been reported that different rout of administration but hydrogel-based Ginsenoside-Rb1 in an OA rabbit model has not been investigated.