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Papers of the Week

January 27, 2023

Br J Anaesth


Phenotype- and species-specific skin proteomic signatures for incision-induced pain in humans and mice.


Segelcke D, van der Burgt M, Kappert C, Schmidt Garcia D, Sondermann JR, Bigalke S, Pradier B, Gomez-Varela D, Zahn PK, Schmidt M, Pogatzki-Zahn EM
Br J Anaesth. 2023 Jan 04.
PMID: 36609060.


Acute pain after surgery is common and often leads to chronic post-surgical pain, but neither treatment nor prevention is currently sufficient. We hypothesised that specific protein networks (protein-protein interactions) are relevant for pain after surgery in humans and mice.