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Papers of the Week


January 27, 2023


J Transl Autoimmun


http://www.ncbi.nlm.nih.gov/pubmed/36683864?dopt=Abstract


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Longitudinal comparison of IL-6, IL-10, and IL-12 cytokine profiles in adult and childhood-onset systemic lupus erythematosus.

Authors

de Peliçari K O, Postal M, Sinicato N A, Londe A C, Fernandes P T, Marini R, Costallat L T L, Appenzeller S
J Transl Autoimmun. 2022; 5:100158.
PMID: 36683864.

Abstract

To compare the levels of Th1 (IL-12) and Th2 (IL-6 and IL10) cytokines over a two-year period among systemic lupus erythematosus patients with childhood-onset (cSLE), adult-onset (sSLE), and healthy controls, and correlate with their clinical, laboratory, and treatment manifestations.