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Papers of the Week


January 27, 2023


Surg Neurol Int


http://www.ncbi.nlm.nih.gov/pubmed/36600729?dopt=Abstract


13

IgG4-related hypophysitis: A monocentric experience from North India.

Authors

Chakraborty A M, Sahoo S K, Chatterjee D, Dutta P, Kumar R, Bhadada S K
Surg Neurol Int. 2022; 13:578.
PMID: 36600729.

Abstract

Immunoglobulin (Ig)G4-related disease is a systemic fibroinflammatory disease characterized by dense infiltration of IgG4-positive plasma cells in the affected tissue(s) with or without elevated plasma levels of IgG4. Hypophysitis itself is a very rare disease with reported prevalence in the operative specimens are around 0.2-0.88%. IgG4-related hypophysitis (IgG4-RH) may account for a substantial percentage of cases previously regarded as idiopathic hypophysitis.