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Papers of the Week


Papers: 17 Dec 2022 - 23 Dec 2022


January 26, 2023


Mod Rheumatol


http://www.ncbi.nlm.nih.gov/pubmed/36537124?dopt=Abstract

CircFOXK2 Promotes the Progression of Osteoarthritis by Regulating the miR-4640-5p/NOTCH2 Axis.

Authors

Shao C, Niu G, Su P, Zhang J, Zhu X, Han G, Xu P, Bai J, Sun K, Sun Y
Mod Rheumatol. 2022 Dec 20.
PMID: 36537124.

Abstract

Osteoarthritis (OA) is the most common age-related chronic and disabling joint disease, frequently causing pain and disability in the adult population. Given that there are no proven disease-modifying drugs for OA, it is urgent to gain a deeper understanding of OA pathogenesis. This study intended to uncover the circFOXK2 regulation in OA.