I am a
Home I AM A Search Login

Papers of the Week


January 27, 2023


In Vivo


http://www.ncbi.nlm.nih.gov/pubmed/36593019?dopt=Abstract


37


1

Age-related Changes in Trigeminal Ganglion Macrophages Enhance Orofacial Ectopic Pain After Inferior Alveolar Nerve Injury.

Authors

Fujiwara S, Urata K, Oto T, Hayashi Y, Hitomi S, Iwata K, Iinuma T, Shinoda M
In Vivo. 2023 Jan-Feb; 37(1):132-142.
PMID: 36593019.

Abstract

The ectopic pain associated with inferior alveolar nerve (IAN) injury has been reported to involve macrophage expression in the trigeminal ganglion (TG). However, the effect of age-related changes on this abnormal pain conditions are still unknown. This study sought to clarify the involvement of age-related changes in macrophage expression and phenotypic conversion in the TG and how these changes enhance ectopic mechanical allodynia after IAN transection (IANX).