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Papers of the Week


2022 Jul


Exp Ther Med


24


1

Possible association between Guillain-Barré syndrome and SARS-CoV-2 infection in children: A case report and literature review.

Authors

Mussinatto I, Benevenuta C, Caci A, Calvo MM, Impastato M, Barra M, Genovese E, Timeus F
Exp Ther Med. 2022 Jul; 24(1):462.
PMID: 35747147.

Abstract

Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in adults and in children, varying from mild to more debilitant symptoms, including fatigue, headache and dizziness. A series of studies have revealed a possible association between Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis at all ages, and SARS-CoV-2 infection. Case reports of novel coronavirus disease 2019 (COVID-19)-associated GBS mainly include adult patients, while only a few pediatric cases have been reported. The present study describes a case of GBS in an Italian 9-year-old girl with previous SARS-CoV-2 infection as a possible trigger, and also conducts a literature review on pediatric COVID-19-associated GBS cases.