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Papers of the Week

2019 Sep 04

Biomed Eng Online



Development of a rule-based automatic five-sleep-stage scoring method for rats.


Wei T-Y, Young C-P, Liu Y-T, Xu J-H, Liang S-F, Shaw F-Z, Kuo C-E
Biomed Eng Online. 2019 Sep 04; 18(1):92.
PMID: 31484584.


Sleep problem or disturbance often exists in pain or neurological/psychiatric diseases. However, sleep scoring is a time-consuming tedious labor. Very few studies discuss the 5-stage (wake/NREM1/NREM2/transition sleep/REM) automatic fine analysis of wake-sleep stages in rodent models. The present study aimed to develop and validate an automatic rule-based classification of 5-stage wake-sleep pattern in acid-induced widespread hyperalgesia model of the rat.