The Clinical Trials SIG will advance and promote the understanding of analgesic clinical trial design. Special attention will be paid to design elements that improve or hinder the assay sensitivity of analgesic investigations. The goals of the SIG will be to:

• Share and disseminate new knowledge regarding clinical trial design that has been previously put forth by other experts in the field 
• Discuss new interventions related to subject training designed to reduce placebo response and/or enhance treatment response
• Discuss techniques for subject education designed to reduce the number of recorded data incongruences within a patient diary
• Evaluate and discuss investigator training initiatives designed to reduce bias and placebo response
• Explore effective techniques for blinded data monitoring designed to identify factors at the research site level that may need correction prior to the end of an investigation
• Foster innovation in the clinical trial process by encouraging the performance, presentation and distribution of methodological post-hoc analysis and by encouraging the prospective inclusion of protocol elements designed to clarify high-priority methodological questions