Cancer Pain: From Molecules to Suffering

Editors: Judith A. Paice, Rae F. Bell, Eija A. Kalso, and Olaitan A. Soyannwo

publish year: 2010
softcover, 354 pages
ISBN-13 978-0-931092-81-7

An in-depth analysis of basic and clinical research on cancer pain, Cancer Pain: From Molecules to Suffering describes underlying mechanisms of cancer pain and reviews opioid treatment issues, including tolerance. This comprehensive new volume discusses current drug trials and research, clinical trial designs, common reactions including inflammation and hyperalgesia, the psychology of cancer pain, and disparities in the availability of cancer care worldwide.

Who should buy this book?
Cancer Pain: From Molecules to Suffering is essential reading for:

• Clinicians, including physicians, nurses, physical therapists, and psychologists
• Cancer researchers interested in studying the mechanisms and psychology of pain, as well as clinical drug trials
• Global health care professionals who experience disparities in cancer treatment
• Medical students who want to improve their skills in cancer pain assessment and management

Table of Contents

Contributing Authors
Foreword
Preface

Part I: Basic Mechanisms of Cancer Pain

1. Mechanisms of Chemotherapy-Induced Neuropathic Pain
   Juan P. Cata, Haijun Zhang, Larry C. Driver, Basem Hamid, Sergio Giralt, Allen W. Burton, and Patrick M. Dougherty
2. Mechanisms of Radiotherapy-Induced Pain Relief
   Yvette M. van der Linden
3. Mechanisms of Malignant Bone Pain
   Patrick Mantyh

Part II: Inflammation, Hyperalgesia, and Cancer Pain

4. Cytokines and Cancer Pain
   Michaela Kress
5. General Inflammatory Reaction and Cachexia in Cancer:Implications for Hyperalgesia
   Marie T. Fallon, Lesley Colvin, and Barry J.A. Laird
6. Opioid-Induced Hyperalgesia and Cancer Pain: Effects on Tumor Growth and Disease Progression
   Tamara King, Frank Porreca, and Todd W. Vanderah

Part III: Opioid Tolerance

7. Mechanisms of Opioid Tolerance
   Charles E. Inturrisi and Ann M. Gregus
8. Opioid Switching: A Technique for Optimizing Pain Relief and Reducing Side Effects in Cancer Pain
   Kris C.P. Vissers, Kees Besse, Yvette M. van der Linden, Maurice Giezeman, and Marieke H.J. van den Beuken-van Everdingen
   
9. Drugs That Act against Opioid Tolerance
   Eija A. Kalso

Part IV: Clinical Trial Design in Cancer Pain

10. New Drugs for Cancer Pain Relief
    Andy Dray
    
11. Methodological Issues in Cancer Pain: Pharmacological Trials
    Ulf E. Kongsgaard and Mads U. Werner
    
12. Methodological Issues in Cancer Pain: Nonpharmacological Trials
    Michael I. Bennett

Part V: Psychology of Cancer Pain: The Basic Research and Clinical Research Agenda

13. Anxiety from an Evolutionary Perspective and the Relationship between Anxiety and Cancer Pain
    Predrag Petrovic
    
14. Dealing with Cancer Pain: Coping, Pain Catastrophizing, and Related Outcomes
    Tamara J. Somers, Francis J. Keefe, Sejal Kothadia, and Agustina Pandiani
15. Attention Management
    Stephen Morley

Part VI: Interaction, Education, Resources: How to Make a Difference

16. Empathy in Cancer Pain
    Amanda C. de C. Williams and Sue Gessler
17. A Global Perspective on Patient and Family Cancer Pain Education
    Jean C. Yi, Samantha B. Artherholt, and Karen L. Syrjala
18. Teaching Medical Students about Cancer Pain
    Karen Forbes and Jane Gibbins
19. Are Research and Clinical Practice Improving Management of Pain in Cancer Patients? Why Do Patients Still Suffer?
    Augusto Caraceni
20. How to Make a Difference in the Developing World: Organizing Resources
    Olaitan A. Soyannwo

Index