|
|
| About IASP | Membership | Meetings | Publications | Chapters | SIGs | Grants | Resources | Professional Development |
|
Attention IASP Members: Pay Your Dues Online Interested in Joining? Learn about Membership  Apply Online Now!
|
|||||||||||||||||||
|
Print This Page |
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Systematic Reviews in Pain Research:
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Editors: Henry J. McQuay, Eija Kalso and R. Andrew Moore publish year: 2008 |
|
Systematic reviews and meta-analyses are powerful tools that can help incorporate the best evidence of the effectiveness of different treatments into health care policy and clinical decisions about individual patients. Systematic Reviews in Pain Research: Methodology Refined, written and edited by experts on evidence-based critical care, anesthesia, and pain management, describes systematic reviews and meta-analyses that estimate the efficacy and harm of interventions in clinical trials of pain medications.
The goals of therapy are changing: not just efficacy is needed, but efficacy in the absence of harm. We need to know not whether interventions work on average, but in which patients they work. This book encourages us to reach out and try to understand clinical research and, more important, to question it.
Table of Contents
| Part I: Systematic Reviews and Meta-Analyses | |
| 1. | Systematic Reviews: Are We Getting It Right Yet? (R. Andrew Moore) |
| 2. | Managing Potential Publication Bias (R. Andrew Moore, Jodie Barden, Sheena Derry, and Henry J. McQuay) |
| 3. | Individual Patient Meta-Analysis (R. Andrew Moore) |
| 4. | Industry Bias (Sheena Derry) |
| 5. | Placebo and Control Event Rate (Henry J. McQuay) |
| 6. | Adverse Events (Sheena Derry) |
| 7. | Guidelines, Guidance, and Evidence (Kate Seers) |
| 8. | Basic Science Systematic Reviews (Vesa K. Kontinen) |
| Part II: Acute Pain | |
| 9. | Treatment of Postoperative Pain: By Procedure Or by
Patient Factors? (Francis Bonnet) |
| 10. | Is Opioid Sparing Clinically Relevant? (Nadia Elia and Martin R. Tramèr) |
| 11. | Challenges in Practicing Evidence-Based Perioperative
Medicine Using Systematic Reviews: What We Know, What Is Uncertain, and
What We Need to Know (Peter Kranke) |
| 12. | What Can We Learn from Evidence on the Use of NSAIDs,
Coxibs, and Paracetamol (Acetaminophen) for Acute Pain? (Emmanuel Marret and Francis Bonnet) |
| 13. | Dose Response (Henry J. McQuay) |
| Part III: Chronic Pain | |
| 14. | Defining the Importance of Change in Clinical Trials of
Acute Pain (Jodie Barden) |
| 15. | Chronic Nonmalignant Pain in the Elderly: Do Opioids
Cause Cognitive Impairment? (Helen Gaskell) |
| 16. | Clinical Trials in Pediatric Pain (Katri Hamunen) |
| 17. | Opioids in Chronic Noncancer Pain: Systematic Reviews
of Efficacy and Safety—What More Is Needed? (Eija Kalso) |
| 18. | Trial Design of Psychological Treatments in Chronic
Pain: What Can We Tell Patients? (Stephen Morley) |
| 19. | Cannabinoids and Analgesia, with Special Reference to
Neuropathic Pain (Andrew S.C. Rice, Isobel Lever, and Roxaneh Zarnegar) |
| 20. | Epidemiology of Chronic Pain (Blair H. Smith and Nicola Torrance) |
| 21. | Cognitive-Behavioral Pain Management: Lessons
Learned (Amanda C. de C. Williams) |
| Part IV: Cancer Pain | |
| 22. | Trial Design in Cancer Pain: Oral Opioids and the Missing Placebo (Rae F. Bell, Torbjørn Wisløff, Christopher Eccleston, and Eija Kalso) |
| 23. | What Evidence Do We Have That the WHO Ladder Is Effective in Cancer Pain? (Michael I. Bennett) |
| Part V: From Evidence to Practice | |
| 24. | What We Have Learned about Trials from Systematic Reviews (Henry J. McQuay) |
| 25. | Risk: Presentation and Systematic Reviews (R. Andrew Moore) |
| 26. | Randomized Controlled Trials for Complex Interventions? (Kate Seers) |
| 27. | Evidence-Based Decision Making: Why Is It So Difficult to Get from
Evidence to Practice? (Steen Møiniche) |
| 28. | Economics: Delivering Better Health Care? (Ceri J. Phillips) |
| 29. | Pain Ladders, Systematic Reviews, and Trials (Henry J. McQuay) |
| 30. | Research Translation for Systematic Reviews into Community Practice:
The Alberta HTA Chronic Pain Ambassador Program (Paul Taenzer, Saifudin Rashiq, Donald Schopflocher, Pamela Barton, Ann Scott, Carmen Moga, and Christa Harstall) |
| Index | |
Reviews
"The editors are three outstanding researchers with a long track
record of excellence in systematic reviews. For this book, they
gathered together a list of authors that read like the
‘who’s who’ of evidence-based medicine in pain
medicine and anaesthesia, including names such as Francis Bonnet,
Emmanuel Marret, Andrew Rice and Martin Tramèr. It is
therefore not surprising that this book is an excellent summary of more
or less everything to do with systematic reviews in pain medicine.
The book addresses the basic methodology by presenting issues such as
industry bias and placebo and control event rate. In the
subsequent parts, it deals with specific issues areas such as acute,
chronic and cancer pain. These topics include the question
‘is opioid sparing clinically relevant?’, reviews of
efficacy and safety of opioids in chronic non-cancer pain and the
question to what extent the effectiveness of the WHO ladder in cancer
pain is evidence based. The final part of the book addresses the
important issue of how to translate from evidence to practice, e.g. how
to get from systematic reviews to community practice in an area such as
chronic pain management.
In conclusion, this is an outstanding book on an extremely important
issue, which should interest anybody working in the area of pain
medicine. While the topic sounds dry, statistical and potentially
boring, the book is actually extremely readable and rather
fascinating. The editors and authors need to be congratulated on
this book, which continues the series of excellent publications by the
International Association for the Study of Pain.”
Anaesthesia and Intensive Care (Volume 37, Number 3,
May 2009), Reviewed by S.A. Schug
"This volume provides detailed insight into the methodological
science of systematic reviews, meta-analyses and clinical trials of
treatment for pain. The book is written by members of a group
known as the International Collaboration of Evidence-Based Critical
Care, Anaesthesia and Pain (ICECAP), working in collaboration with the
International Association for the Study of Pain (IASP). The book
is divided into five sections; Systematic Reviews and Meta-Analyses,
Acute Pain, Chronic Pain, Cancer Pain, and From Evidence to
Practice. Any one with an interest in the continually evolving
methodological issues and how we should interpret the results of reviews
and trials in clinical practice will enjoy this book."
e-Newsletter from the International Association for Hospice and
Palliative Care, reviewed by Roger Woodruff, April 2008